We all know those evidence linking OSA to systemic hypertension (even if your patient is not obese), because the vasoconstriction and activation of renin-angiotensin-aldosterone axis. But now there is new evidence that OSA is an important risk factor for stroke.
A new observational cohort study of NEJM by Yaggi et al, states that OSA increases significantly the risk of stroke, TIA or sudden death.
REFERENCES:
Yaggi HK, Concato J, Kernan WN, Lichtman JH, Brass LM, Mohsenin V.Obstructive sleep apnea as a risk factor for stroke and death. N Engl JMed 2005;353:2034-2041.
Regards,
Jon Mikel Iñarritu, M.D.
technorati tags: sleep obstructive apnea, stroke, death, OSA, NEJM, medical articles, Yaggi, medicine, unbounded medicine, sleep disorders
This is a clinical case presentation of a patient with OSA to illustrate the study.